What Is
It?
Scleroderma (sclaire-row-DER-ma)
is a disease that can cause
thickening, hardening, or
tightening of the skin, blood
vessels and internal organs.
Scleroderma is chronic, which
means it can last a long time.
There are two types of
scleroderma:
- Localized scleroderma
mainly affects the skin.
There are two types of
localized scleroderma:
- Morphia (hard, oval
shaped patches on the
skin. The patches
usually are whitish with
a purplish ring around
them.)
- Linear (lines or
streaks of thickened
skin in areas such as
the arms, legs or
forehead.)
- Generalized scleroderma
may affect many parts of the
body. There are two types of
generalized scleroderma:
- Limited scleroderma
occurs gradually and
affects the skin and
later may affect
internal organs, such as
esophagus, lungs or
intestines.
- Diffuse scleroderma
develops more suddenly,
with skin thickening
throughout the body.
Internal organs can also
be affected.
What Are the Symptoms?
- Skin changes:
- Hardening and
thickening
- Ulcers or sores on
fingers
- Loss of hair over
affected area
- Change in skin color
- Swelling/puffiness
in fingers/toes
- Skin appears shiny.
- Usually skin creases
disappear.
- Difficulty making a fist
- Sclerodactyly (hardness
of toes/hands)
- Raynaud's Phenomenon:
- Poor blood flow to
extremities.
- Extremities are
sensitive to cold caused
by emotional stress.
- Telangiectasia (tiny
blood vessels seen at
the surface of the
skin).
- Calcinosis (white
calcium lumps under the
skin)
- Arthritis and muscle
weakness
- Sjogren's syndrome
(dryness of eyes/mouth)
- Digestive problems
- Heart and lung problems
- Kidney problems
What
Causes It?
Although the cause is unknown,
it is known that the body
produces too much of a protein
called collagen. Excess collagen
is deposited causing thickening
and hardening.
How Is It Diagnosed?
Physical exam, medical history
and lab tests which may include
biopsy and blood tests.
Treatment Options
Although there is no cure, many
different drugs can help control
it. Treatments may include:
- Medications:
NSAIDs/aspirin for
inflammation and pain,
steroids to treat
muscle/joint problems,
antacids to reduce
heartburn, medication to
control blood pressure and
to increase blood flow
- Exercise to improve
overall health.
- Joint protection to
reduce stress on joints.
- Skin protection to
protect skin from injury.
- Stress management -
common with chronic disease.
Who
Is At Risk?
The disease usually affects
adults between the ages of 30
and 50, and more women than men. |